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Whilst lower-rely MBL seldom progresses to CLL, higher-count MBL progresses to CLL demanding therapy at a amount of 1% to 2% per annum. Large-depend MBL is distinguished from Rai 0 CLL depending on whether or not the B-cell rely is higher than or under five × 109/L. Although men and women with both large-depend MBL and CLL Rai stage 0 are at impro